Atorvastatin-DBCO

Atorvastatin-DBCO is a novel bioorthogonal conjugate designed specifically for click chemistry mediated copper free labeling and targeted delivery studies. This compound utilizes the extremely high reactivity of DBCO groups to undergo rapid and specific cycloaddition reactions with azides (Azide) without the need for catalysts, thereby accurately "mounting" atorvastatin onto biomolecules (such as antibodies, polysaccharides) or nanocarriers containing azide groups. This design aims to preserve the pleiotropic pharmacological effects of atorvastatin in regulating blood lipids, anti-inflammatory, and stabilizing plaques, while endowing it with traceability or targeting. It is a cutting-edge tool molecule in the study of cardiovascular drug delivery mechanisms.

msds of Atorvastatin-DBCO